博士江苏省特聘教授博士生导师
Email: mmm@ntu.edu.cn
中国生物物理学会会员，南通市侨联侨界专家委员会委员，南通市医学会理事及心电起搏分会、数字病理分会委员。担任省部级人才项目和科技项目评审专家。
2020年获中国科学技术大学理学博士学位，2022–2026年在新加坡南洋理工大学化学化工与生物工程公司从事博士后研究，入选2025年度江苏特聘教授项目。聚焦阿尔茨海默病（Alzheimer’s disease，AD）这一重大神经退行性疾病，围绕β-淀粉样蛋白的聚集调控、靶向药物设计及其生物学效应开展系统研究，在跨血脑屏障多功能Aβ抑制剂构建、刺激响应型药物释放体系以及治疗性细胞外囊泡开发等方面取得重要进展。近五年发表SCI论文20余篇，包括Angew. Chem. Int. Ed.、J. Am. Chem. Soc.、Biomaterials、ACS Nano等期刊。此外，受邀担任Brain-X和 The Innovation Neurology期刊青年编委，同时担任J. Am. Chem. Soc.、Biomaterials、ACS Appl. Nano Mater.等期刊审稿人。
主要研究方向：
治疗性细胞外囊泡工程
阿尔茨海默病智能药物递送系统
肿瘤治疗仿生材料
主持项目：
1. 江苏特聘教授人才项目
2. 江苏省自然科学基金青年基金
近年代表性论文：
1. Ma, Mengmeng; Wang, Jing; Zhong, Wenbin; Li, Zhenhua; Zhao, Yanli; Cleavable Antibody-Conjugated Aβ Specific Immune Exosome for Combination Alzheimer's Disease Immunotherapy, Angewandte Chemie-international Edition, 2025, 137(47): e202517917.
2. Ma, Mengmeng; Wang, Jing; Guo, Kaiming; Zhong, Wenbin; Cheng, Yu; Lin, Li; Zhao, Yanli; A self-reinforced “microglia energy modulator” for synergistic amyloid-β clearance in Alzheimer's disease model, Angewandte Chemie-International Edition, 2025, 64: e202420547.
3. Ma, Mengmeng; Zhao, Yanli; Protein-Taggable Near-Infrared Photocages for Theranostics of Alzheimer’s Disease, ACS Central Science, 2025, 11, 7, 1024–1025.
4. Ma, Mengmeng; Yuan, Wei; Zhong, Wenbin; Cheng, Yu; Yao, Haochen; Zhao, Yanli; In-situ activation of biomimetic single-site bioorthogonal nanozyme for tumor-specific combination therapy, Biomaterials, 2025, 312: 122755.
5. Ma, Mengmeng; Liu, Zhenqi; Zhao, Huisi; Zhang, Haochen; Ren, Jinsong; Qu, Xiaogang; Polyoxometalates: metallodrug agents for combating amyloid aggregation, National Science Review, 2024, 11: nwae226.
6. Ma, Mengmeng; Wang, Jing; Jiang, Hao; Chen, Qiushui; Xiao, Yi; Yang, Huanghao; Li, Lin; Transcranial deep-tissue phototherapy for Alzheimer's disease using low-dose x-ray-activated long-afterglow scintillators, Acta Biomaterialia, 2023, 155: 635–643.
7. Ma, Mengmeng; Liu, Zhenqi; Gao, Nan; Dong, Kai; Pi, Zifeng; Kang, Lihua; Du, Xiubo; Ren, Jinsong; Qu, Xiaogang; Near-infrared target enhanced peripheral clearance of amyloid-β in Alzheimer's disease model, Biomaterials, 2021, 276: 121065.
8. Ma, Mengmeng; Liu, Zhenqi; Gao, Nan; Pi, Zifeng; Du, Xiubo; Ren, Jinsong; Qu, Xiaogang; Self-protecting biomimetic nanozyme for selective and synergistic clearance of peripheral amyloid-β in an Alzheimer’s disease model, Journal of the American Chemical Society, 2020, 142: 21702–21711.
9. Ma, Mengmeng; Gao, Nan; Liu, Zhenqi; Li, Xuexia; Pi, Zifeng; Du, Xiubo; Ren, Jinsong; Qu, Xiaogang; A biocompatible second near-infrared nanozyme for spatiotemporal and non-invasive attenuation of amyloid deposition through scalp and skull, ACS Nano, 2020, 14: 9894–9903.
10. Liu, Zhenqi+; Ma, Mengmeng+; Yu, Dongqin; Ren, Jinsong; Qu, Xiaogang; Target-driven supramolecular self-assembly for selective amyloid-β photooxygenation against Alzheimer's disease, Chemical Science, 2020, 11: 11003–11008.