顾锡娟
博士讲师
Email: xijuangu@ntu.edu.cn
顾锡娟，博士，讲师。2026年博士毕业于365英国上市公司。主要从事CRISPR分子诊断、生物传感与公共卫生快速检测等方面研究。主要包括 CRISPR/Cas与核酸等温扩增技术、光热与荧光生物传感平台构建、便携式即时检测装置与智能手机联用系统开发、AI图像识别算法在临床检测中的应用，以及食源性致病菌、呼吸道病原体和肝炎病毒的快速、灵敏、可视化检测。主持和参与南通市科技计划项目、江苏省基础研究计划（自然科学基金）、江苏省高校自然科学研究项目；为江苏省“青蓝工程”优秀青年骨干教师。在国际著名学术期刊上发表SCI论文十余篇，其中第一作者四篇，发明专利两项。
代表学术论文：
2026年度
1. X. Gu, T. Wang, L. Wu, J. Guan, X. Kang, W. Ming, Y. Zhu, Q. Xu, Y. Qin and L. Wu, Enhanced detection of HBV and HCV using Cas13a-FLAP and FGoAI platforms, Chem. Sci., 2026, 17, 1656-1665.IF: 7.5, SCI一区.
2025年度
1.A. Pan, X. Gu, W. Ming, J. Zhang, W. Jiang, Y. Zhang, S. Wang, Y. Qin and L. Wu, miRNA biomarkers: advancing early detection of acute myocardial infarction, Microchim. Acta., 2025, 192, 500. IF: 5.1, SCI二区.
2.X. Kang, J. Yuan, X. Gu, X. Li, T. Wen, M. He, Y. He, X. Yang, Y. Li, C. Guo, H. Ji, Y. Qin and L. Wu, DNA-templated Ag nanocluster/CdSe@ZnS quantum dot-based platform for colorimetric and fluorescence detection of organophosphorus pesticide, ACS Appl. Nano Mater., 2025, 8, 1663-1672. IF: 5.5, SCI二区.
3.L. Zhu, M. Yang, Q. Tang, Q. Wang, X. Gu, X. Kong, L. Wu and Y. Qin, Highly efficient dual-probe strategy toward single-cell metabolite analysis, Anal. Chem., 2025, 97, 703-711.IF: 6.8, SCI一区.
4.W. Jiang, Y. Zhu, Q. Tang, X. Kang, H. Ji, C. Guo, X. Gu, J. Zhang, Z. Mao, L. Wu and Y. Qin, On-site detection of OTA and AFB1 based on branched hybridization chain reaction coupled with lateral flow assay, Talanta., 2025, 283, 127095. IF: 5.9, SCI一区.
2024年度
1.X. Gu, A. Pan, L. Wu, J. Zhang, Z. Xu, T. Wen, M. Wang, X. Shi, L. Wu and Y. Qin, Multiplexed detection of respiratory pathogens using a portable device combining a CREM strategy, Chem. Sci., 2024, 15, 18411-18418. IF: 7.5, SCI一区.
2.X. Gu, Q. Tang, Y. Zhu, C. Sun, L. Wu, H. Ji, Q. Wang, L. Wu and Y. Qin, Advancements of CRISPR technology in public health-related analysis, Biosens. Bioelectron., 2024, 261, 116449. IF: 11.8, SCI一区.
3.X. Gu, Q. Tang, X. Kang, H. Ji, X. Shi, L. Shi, A. Pan, Y. Zhu, W. Jiang, J. Zhang, J. Liu, M. Wu, L. Wu and Y. Qin, A portable CRISPR-Cas12a triggered photothermal biosensor for sensitive and visual detection of Staphylococcus aureus and Listeria monocytogenes, Talanta., 2024, 271, 125678. IF: 5.9, SCI一区.
4.L. Yang, X. Gu, J. Liu, L. Wu and Y. Qin, Functionalized nanomaterials-based electrochemiluminescent biosensors and their application in cancer biomarkers detection, Talanta., 2024, 267, 125237. IF: 5.9, SCI一区.
5.Y. Zhu, X. Gu, Q. Tang, W. Jiang, R. Xia, J. Zhang, H. Ji, Y. Qin and L. Wu, HCR-assisted RTF-EXPAR-based lateral flow analysis for sensitive detection of H1N1 influenza virus, Anal. Chem., 2024, 96, 14116-14124. IF: 6.8, SCI一区.
6.W. Jiang, Q. Tang, Y. Zhu, X. Gu, L. Wu and Y. Qin, Research progress of microfluidics-based food safety detection, Food Chem., 2024, 441, 138319. IF: 10.4, SCI一区.
2023年度
1. 蒋汶君, 唐曲, 顾锡娟, 冀海伟, 吴丽和秦玉岭, 基于微流控技术的疾病标志物即时检测研究进展, 分析化学, 2023, 51, 1403-1413. IF: 1.3, SCI三区.
2.G. Li, M. Wu, Y. Xu, Q. Wang, J. Liu, X. Zhou, H. Ji, Q. Tang, X. Gu, S. Liu, Y. Qin, L. Wu and Q. Zhao, Recent progress in the development of singlet oxygen carriers for enhanced photodynamic therapy, Coord. Chem. Rev., 2023, 478, 214979. IF: 25.5, SCI一区.